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both claims and ehr data iqvia adjudicated health plan claims data  (IQVIA Inc)
90
IQVIA Inc both claims and ehr data iqvia adjudicated health plan claims data
Both Claims And Ehr Data Iqvia Adjudicated Health Plan Claims Data, supplied by IQVIA Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/merativetm+(ccae)+marketscan%C2%AE+commercial+database/both+claims+and+ehr+data+iqvia+adjudicated+health+plan+claims+data/pmc11839857-58-84-87
Average 90 stars, based on 1 article reviews
both claims and ehr data iqvia adjudicated health plan claims data - by Bioz Stars, 2026-10
90/100 stars
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electronic health records johns hopkins medicine  (Johns Hopkins HealthCare)
90
Johns Hopkins HealthCare electronic health records johns hopkins medicine
Electronic Health Records Johns Hopkins Medicine, supplied by Johns Hopkins HealthCare, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/merativetm+(ccae)+marketscan%C2%AE+commercial+database/johns+hopkins+health+system+automated+databases/pmc11839857-58-76-76
Average 90 stars, based on 1 article reviews
electronic health records johns hopkins medicine - by Bioz Stars, 2026-10
90/100 stars
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ambulatory electronic medical records  (IQVIA Inc)
90
IQVIA Inc ambulatory electronic medical records
<t>Empirical</t> equipoise, covariate balance, empirical calibration validity diagnostics and representativeness for <t>IBD</t> primary analysis Key: Amb EMR = IQVIA Ambulatory Electronic Medical Records; ASMD = absolute standardized mean difference; CCAE = Merative™ MarketScan ® Commercial Database; CI = Confidence Interval; Clinformatics ® = Optum ® De-Identified Clinformatics ® Data Mart Database; EASE = expected absolute systematic error; HR = Hazard ratio; IBD = irritable bowel diseases (Crohn’s disease or ulcerative colitis); IBD comparator = golimumab, certolizumab pegol, ustekinumab, or vedolizumab; Optum ® EHR = Optum ® De-Identified Electronic Health Record; Pharmetrics = IQVIA Adjudicated Health Plan Claims Data; Remicade ® (m) = Remicade ® exposure; Target covariate prevalence = prevalence of baseline covariates in the initial Remicade ® exposure cohort before study design restrictions were applied; Analytic covariate prevalence = prevalence of baseline covariates in Remicade ® exposure cohort after study design restrictions were applied (i.e., PS matching)
Ambulatory Electronic Medical Records, supplied by IQVIA Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/merativetm+(ccae)+marketscan%C2%AE+commercial+database/ambulatory+electronic+medical+records/pmc11681708-228-13-20
Average 90 stars, based on 1 article reviews
ambulatory electronic medical records - by Bioz Stars, 2026-10
90/100 stars
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Empirical equipoise, covariate balance, empirical calibration validity diagnostics and representativeness for IBD primary analysis Key: Amb EMR = IQVIA Ambulatory Electronic Medical Records; ASMD = absolute standardized mean difference; CCAE = Merative™ MarketScan ® Commercial Database; CI = Confidence Interval; Clinformatics ® = Optum ® De-Identified Clinformatics ® Data Mart Database; EASE = expected absolute systematic error; HR = Hazard ratio; IBD = irritable bowel diseases (Crohn’s disease or ulcerative colitis); IBD comparator = golimumab, certolizumab pegol, ustekinumab, or vedolizumab; Optum ® EHR = Optum ® De-Identified Electronic Health Record; Pharmetrics = IQVIA Adjudicated Health Plan Claims Data; Remicade ® (m) = Remicade ® exposure; Target covariate prevalence = prevalence of baseline covariates in the initial Remicade ® exposure cohort before study design restrictions were applied; Analytic covariate prevalence = prevalence of baseline covariates in Remicade ® exposure cohort after study design restrictions were applied (i.e., PS matching)

Journal: BMC Medical Research Methodology

Article Title: The necessity of validity diagnostics when drawing causal inferences from observational data: lessons from a multi-database evaluation of the risk of non-infectious uveitis among patients exposed to Remicade ®

doi: 10.1186/s12874-024-02428-7

Figure Lengend Snippet: Empirical equipoise, covariate balance, empirical calibration validity diagnostics and representativeness for IBD primary analysis Key: Amb EMR = IQVIA Ambulatory Electronic Medical Records; ASMD = absolute standardized mean difference; CCAE = Merative™ MarketScan ® Commercial Database; CI = Confidence Interval; Clinformatics ® = Optum ® De-Identified Clinformatics ® Data Mart Database; EASE = expected absolute systematic error; HR = Hazard ratio; IBD = irritable bowel diseases (Crohn’s disease or ulcerative colitis); IBD comparator = golimumab, certolizumab pegol, ustekinumab, or vedolizumab; Optum ® EHR = Optum ® De-Identified Electronic Health Record; Pharmetrics = IQVIA Adjudicated Health Plan Claims Data; Remicade ® (m) = Remicade ® exposure; Target covariate prevalence = prevalence of baseline covariates in the initial Remicade ® exposure cohort before study design restrictions were applied; Analytic covariate prevalence = prevalence of baseline covariates in Remicade ® exposure cohort after study design restrictions were applied (i.e., PS matching)

Article Snippet: Fig. 1 Empirical equipoise, covariate balance, empirical calibration validity diagnostics and representativeness for IBD primary analysis Key: Amb EMR = IQVIA Ambulatory Electronic Medical Records; ASMD = absolute standardized mean difference; CCAE = MerativeTM MarketScan ® Commercial Database; CI = Confidence Interval; Clinformatics ® = Optum ® De-Identified Clinformatics ® Data Mart Database; EASE = expected absolute systematic error; HR = Hazard ratio; IBD = irritable bowel diseases (Crohn’s disease or ulcerative colitis); IBD comparator = golimumab, certolizumab pegol, ustekinumab, or vedolizumab; Optum ® EHR = Optum ® De-Identified Electronic Health Record; Pharmetrics = IQVIA Adjudicated Health Plan Claims Data; Remicade ® (m) = Remicade ® exposure; Target covariate prevalence = prevalence of baseline covariates in the initial Remicade ® exposure cohort before study design restrictions were applied; Analytic covariate prevalence = prevalence of baseline covariates in Remicade ® exposure cohort after study design restrictions were applied (i.e., PS matching) Fig. 2 Empirical equipoise, covariate balance, empirical calibration validity diagnostics and representativeness for RA primary analysis Key – Target: patients with inflammatory bowel diseases newly exposed to Remicade ® , Comparator: patients with inflammatory bowel diseases newly exposed to [golimumab, certolizumab pegol, ustekinumab, or vedolizumab], CCAE: MerativeTM MarketScan ® Commercial Database, Optum ® EHR = Optum ® De-Identified Electronic Health Record; Pharmetrics = IQVIA Adjudicated Health Plan Claims Data Figure depicts the same diagnostics information as Fig. but for the comparisons in the RA study population.

Techniques:

Attrition diagrams for inflammatory bowel diseases (IBD); patient attrition counts and proportions after sequential design choices applied Key: Amb EMR = IQVIA Ambulatory Electronic Medical Records; ASMD = absolute standardized mean difference; CCAE = Merative™ MarketScan ® Commercial Database; CI = Confidence Interval; Clinformatics ® = Optum ® De-Identified Clinformatics ® Data Mart Database; EASE = expected absolute systematic error; HR = Hazard ratio; Optum ® EHR = Optum ® De-Identified Electronic Health Record; Pharmetrics = IQVIA Adjudicated Health Plan Claims Data; RA = rheumatoid arthritis; RA comparator = certolizumab pegol or tocilizumab; Remicade ® (m) = Remicade ® exposure with concurrent methotrexate; Target covariate prevalence = prevalence of baseline covariates in the initial Remicade ® exposure cohort before study design restrictions were applied; Analytic covariate prevalence = prevalence of baseline covariates in Remicade ® exposure cohort after study design restrictions were applied (i.e., PS matching)

Journal: BMC Medical Research Methodology

Article Title: The necessity of validity diagnostics when drawing causal inferences from observational data: lessons from a multi-database evaluation of the risk of non-infectious uveitis among patients exposed to Remicade ®

doi: 10.1186/s12874-024-02428-7

Figure Lengend Snippet: Attrition diagrams for inflammatory bowel diseases (IBD); patient attrition counts and proportions after sequential design choices applied Key: Amb EMR = IQVIA Ambulatory Electronic Medical Records; ASMD = absolute standardized mean difference; CCAE = Merative™ MarketScan ® Commercial Database; CI = Confidence Interval; Clinformatics ® = Optum ® De-Identified Clinformatics ® Data Mart Database; EASE = expected absolute systematic error; HR = Hazard ratio; Optum ® EHR = Optum ® De-Identified Electronic Health Record; Pharmetrics = IQVIA Adjudicated Health Plan Claims Data; RA = rheumatoid arthritis; RA comparator = certolizumab pegol or tocilizumab; Remicade ® (m) = Remicade ® exposure with concurrent methotrexate; Target covariate prevalence = prevalence of baseline covariates in the initial Remicade ® exposure cohort before study design restrictions were applied; Analytic covariate prevalence = prevalence of baseline covariates in Remicade ® exposure cohort after study design restrictions were applied (i.e., PS matching)

Article Snippet: Fig. 1 Empirical equipoise, covariate balance, empirical calibration validity diagnostics and representativeness for IBD primary analysis Key: Amb EMR = IQVIA Ambulatory Electronic Medical Records; ASMD = absolute standardized mean difference; CCAE = MerativeTM MarketScan ® Commercial Database; CI = Confidence Interval; Clinformatics ® = Optum ® De-Identified Clinformatics ® Data Mart Database; EASE = expected absolute systematic error; HR = Hazard ratio; IBD = irritable bowel diseases (Crohn’s disease or ulcerative colitis); IBD comparator = golimumab, certolizumab pegol, ustekinumab, or vedolizumab; Optum ® EHR = Optum ® De-Identified Electronic Health Record; Pharmetrics = IQVIA Adjudicated Health Plan Claims Data; Remicade ® (m) = Remicade ® exposure; Target covariate prevalence = prevalence of baseline covariates in the initial Remicade ® exposure cohort before study design restrictions were applied; Analytic covariate prevalence = prevalence of baseline covariates in Remicade ® exposure cohort after study design restrictions were applied (i.e., PS matching) Fig. 2 Empirical equipoise, covariate balance, empirical calibration validity diagnostics and representativeness for RA primary analysis Key – Target: patients with inflammatory bowel diseases newly exposed to Remicade ® , Comparator: patients with inflammatory bowel diseases newly exposed to [golimumab, certolizumab pegol, ustekinumab, or vedolizumab], CCAE: MerativeTM MarketScan ® Commercial Database, Optum ® EHR = Optum ® De-Identified Electronic Health Record; Pharmetrics = IQVIA Adjudicated Health Plan Claims Data Figure depicts the same diagnostics information as Fig. but for the comparisons in the RA study population.

Techniques:

Empirical equipoise, covariate balance, empirical calibration validity diagnostics and representativeness for RA primary analysis Key – Target: patients with inflammatory bowel diseases newly exposed to Remicade ® , Comparator: patients with inflammatory bowel diseases newly exposed to [golimumab, certolizumab pegol, ustekinumab, or vedolizumab], CCAE: Merative™ MarketScan ® Commercial Database, Optum ® EHR = Optum ® De-Identified Electronic Health Record; Pharmetrics = IQVIA Adjudicated Health Plan Claims Data

Journal: BMC Medical Research Methodology

Article Title: The necessity of validity diagnostics when drawing causal inferences from observational data: lessons from a multi-database evaluation of the risk of non-infectious uveitis among patients exposed to Remicade ®

doi: 10.1186/s12874-024-02428-7

Figure Lengend Snippet: Empirical equipoise, covariate balance, empirical calibration validity diagnostics and representativeness for RA primary analysis Key – Target: patients with inflammatory bowel diseases newly exposed to Remicade ® , Comparator: patients with inflammatory bowel diseases newly exposed to [golimumab, certolizumab pegol, ustekinumab, or vedolizumab], CCAE: Merative™ MarketScan ® Commercial Database, Optum ® EHR = Optum ® De-Identified Electronic Health Record; Pharmetrics = IQVIA Adjudicated Health Plan Claims Data

Article Snippet: Fig. 1 Empirical equipoise, covariate balance, empirical calibration validity diagnostics and representativeness for IBD primary analysis Key: Amb EMR = IQVIA Ambulatory Electronic Medical Records; ASMD = absolute standardized mean difference; CCAE = MerativeTM MarketScan ® Commercial Database; CI = Confidence Interval; Clinformatics ® = Optum ® De-Identified Clinformatics ® Data Mart Database; EASE = expected absolute systematic error; HR = Hazard ratio; IBD = irritable bowel diseases (Crohn’s disease or ulcerative colitis); IBD comparator = golimumab, certolizumab pegol, ustekinumab, or vedolizumab; Optum ® EHR = Optum ® De-Identified Electronic Health Record; Pharmetrics = IQVIA Adjudicated Health Plan Claims Data; Remicade ® (m) = Remicade ® exposure; Target covariate prevalence = prevalence of baseline covariates in the initial Remicade ® exposure cohort before study design restrictions were applied; Analytic covariate prevalence = prevalence of baseline covariates in Remicade ® exposure cohort after study design restrictions were applied (i.e., PS matching) Fig. 2 Empirical equipoise, covariate balance, empirical calibration validity diagnostics and representativeness for RA primary analysis Key – Target: patients with inflammatory bowel diseases newly exposed to Remicade ® , Comparator: patients with inflammatory bowel diseases newly exposed to [golimumab, certolizumab pegol, ustekinumab, or vedolizumab], CCAE: MerativeTM MarketScan ® Commercial Database, Optum ® EHR = Optum ® De-Identified Electronic Health Record; Pharmetrics = IQVIA Adjudicated Health Plan Claims Data Figure depicts the same diagnostics information as Fig. but for the comparisons in the RA study population.

Techniques:

Risk of non-infectious uveitis (NIU) among patients with inflammatory bowel diseases (IBD) Key – PS: propensity score, OT: on-treatment, ITT: intention-to-treat, T: Remicade ® new users with IBD, C: golimumab, certolizumab pegol, ustekinumab, or vedolizumab new users with IBD, IR: incidence rate, PYs: person-years, CCAE: Merative™ MarketScan ® Commercial Database, Optum ® EHR: Optum ® De-Identified Electronic Health Record, Pharmetrics: IQVIA Adjudicated Health Plan Claims Data

Journal: BMC Medical Research Methodology

Article Title: The necessity of validity diagnostics when drawing causal inferences from observational data: lessons from a multi-database evaluation of the risk of non-infectious uveitis among patients exposed to Remicade ®

doi: 10.1186/s12874-024-02428-7

Figure Lengend Snippet: Risk of non-infectious uveitis (NIU) among patients with inflammatory bowel diseases (IBD) Key – PS: propensity score, OT: on-treatment, ITT: intention-to-treat, T: Remicade ® new users with IBD, C: golimumab, certolizumab pegol, ustekinumab, or vedolizumab new users with IBD, IR: incidence rate, PYs: person-years, CCAE: Merative™ MarketScan ® Commercial Database, Optum ® EHR: Optum ® De-Identified Electronic Health Record, Pharmetrics: IQVIA Adjudicated Health Plan Claims Data

Article Snippet: Fig. 1 Empirical equipoise, covariate balance, empirical calibration validity diagnostics and representativeness for IBD primary analysis Key: Amb EMR = IQVIA Ambulatory Electronic Medical Records; ASMD = absolute standardized mean difference; CCAE = MerativeTM MarketScan ® Commercial Database; CI = Confidence Interval; Clinformatics ® = Optum ® De-Identified Clinformatics ® Data Mart Database; EASE = expected absolute systematic error; HR = Hazard ratio; IBD = irritable bowel diseases (Crohn’s disease or ulcerative colitis); IBD comparator = golimumab, certolizumab pegol, ustekinumab, or vedolizumab; Optum ® EHR = Optum ® De-Identified Electronic Health Record; Pharmetrics = IQVIA Adjudicated Health Plan Claims Data; Remicade ® (m) = Remicade ® exposure; Target covariate prevalence = prevalence of baseline covariates in the initial Remicade ® exposure cohort before study design restrictions were applied; Analytic covariate prevalence = prevalence of baseline covariates in Remicade ® exposure cohort after study design restrictions were applied (i.e., PS matching) Fig. 2 Empirical equipoise, covariate balance, empirical calibration validity diagnostics and representativeness for RA primary analysis Key – Target: patients with inflammatory bowel diseases newly exposed to Remicade ® , Comparator: patients with inflammatory bowel diseases newly exposed to [golimumab, certolizumab pegol, ustekinumab, or vedolizumab], CCAE: MerativeTM MarketScan ® Commercial Database, Optum ® EHR = Optum ® De-Identified Electronic Health Record; Pharmetrics = IQVIA Adjudicated Health Plan Claims Data Figure depicts the same diagnostics information as Fig. but for the comparisons in the RA study population.

Techniques: